Role of adrenergic and histaminergic systems in clonidine-induced inhibition of the pinnal reflex in mice.
نویسندگان
چکیده
Clonidine is reported to inhibit the az-adrenoceptor mediated pinnal reflex in mice (3). Clonidine produces its effect by acting as an oc2-adrenergic autoreceptor agonist (1). As such, clonidine is also agonist for presynaptic histamine Hz-receptors (8). To test whether the clonidine-induced inhibition of the pinnal reflex is mediated through adrenergic and/or histaminergic system, the interaction of agents influencing adrenergi,c and histaminergic systems was studied in experiments involving this reflex.
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ورودعنوان ژورنال:
- Indian journal of physiology and pharmacology
دوره 28 2 شماره
صفحات -
تاریخ انتشار 1984